Since the team members live and work far apart in different countries, we use OWA for the e-mail and have HelpDesk OSP installed on a server where Outlook is running 24/7. We can always access the tickets from our smartphones, which is a big advantage for those of us who travel a lot.
Even if we don't use all the possibilities SharePoint gives - because we don't need them - we are very satisfied with our software and with having this connection between our e-mail and our intranet. Since we often get questions about how to use HelpDesk OSP for a distributed group, we have made a faq that explains how we have set it up. Welcome to read more about our way of using HelpDesk OSP!